A unified approach to the daucane and sphenolobane bicyclo[5.3.0]decane core: enantioselective total syntheses of daucene, daucenal, epoxydaucenal B, and 14-para-anisoyloxydauc-4,8-diene.
نویسندگان
چکیده
Access to the bicyclo[5.3.0]decane core found in the daucane and sphenolobane terpenoids via a key enone intermediate enables the enantioselective total syntheses of daucene, daucenal, epoxydaucenal B, and 14-para-anisoyloxydauc-4,8-diene. Central aspects include a catalytic asymmetric alkylation followed by a ring contraction and ring-closing metathesis to generate the five- and seven-membered rings, respectively.
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ورودعنوان ژورنال:
- Chemistry
دوره 19 52 شماره
صفحات -
تاریخ انتشار 2013